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, 1994). CoVs genomic RNA replication is mediated by RNA-directed RNA polymerase (Pol/RdRp) which happens to be also chargeable for transcription from the viral RNA genome. There's experimental evidence for SARS-CoV that nsp7 and nsp8 activate and confer processivity to the RNA-synthesizing exercise from the polymerase (partitions et al., 2000). Th